Doctor Jowl, often referred to as "The Great Doctor Jowl" is a wise hermit that lives in the Ash Desert. He is from the same species as Tallow, and employed him as an indentured servant for many years for an unknown reason. Their exact relation is unclear, though they maintain a playfully hateful relationship.

Once he is able to help Drift start her new journey, he claims to have fulfilled his final purpose, the thing that kept him alive so unusually long. He finally passes away after advising her to travel to the Heart of the Universe.